Simvastatin EP impurity F

SL-4393

Simvastatin EP impurity F, >98%

CAS No. : [79952-44-6]

Synonyms : Simvastatin USP related compound F; Lovastatin epimer; epi-Lovastatin

IUPAC Name : (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (R)-2-methylbutanoate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : This is an impurity of Simvastatin (Simvastatin EP impurity F), which is a competitive inhibitor of HMG-CoA reductase. It is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk.

References : Slater E. E. et al.: Drugs. 36 Suppl 3, 72-82, 1988; Kureishi Y. et al.: Nat Med, 6(9), 1004-1010, 2000; Leung B. P. et al. J Immunol, 170(3), 1524-1530, 2003; Kobayashi M. et al.: J. Pharmacol, 49(1), 125-133, 1989; Ishida F. et al.: Biochim Biophys Acta, 1042(3), 365-373, 1990; Sukhova G. K. et al. Arterioscler Thromb Vasc Biol, 22(9), 1452-1458, 2002; Dansette P. M. et al.: Exp. Toxicol Pathol, 52(2), 145-148, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.