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Simvastatin hydroxy acid ammonium salt

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SL-4388

Simvastatin hydroxy acid ammonium salt, >98%

CAS No. : [139893-43-9]

IUPAC Name : Ammonium (3R,5R)-7-((1S,2S,6R,8S,8aR)-8-((2,2-dimethylbutanoyl)oxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G45.00
Back Order  Estimated to ship on 04 October 2026
5G145.00
Back Order  Estimated to ship on 04 October 2026
10G245.00
Back Order  Estimated to ship on 04 October 2026
25G525.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H43NO6
Mol. Weight :
453.62
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Simvastatin, which is a competitive inhibitor of HMG-CoA reductase. It is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk.

References : Slater E. E. et al.: Drugs. 36 Suppl 3, 72-82, 1988; Kureishi Y. et al.: Nat Med, 6(9), 1004-1010, 2000; Leung B. P. et al. J Immunol, 170(3), 1524-1530, 2003; Kobayashi M. et al.: J. Pharmacol, 49(1), 125-133, 1989; Ishida F. et al.: Biochim Biophys Acta, 1042(3), 365-373, 1990; Sukhova G. K. et al. Arterioscler Thromb Vasc Biol, 22(9), 1452-1458, 2002; Dansette P. M. et al.: Exp. Toxicol Pathol, 52(2), 145-148, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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