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Siponimod alcohol impurity

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Siponimod alcohol impurity, >98%

CAS No. : [1418144-66-7]

IUPAC Name : (E)-1-(3-Ethyl-4-(hydroxymethyl)phenyl)ethan-1-one O-(4-cyclohexyl-3-(trifluoromethyl)benzyl) oxime

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Chemical Properites
Mol. Formula :
C25H30F3NO2
Mol. Weight :
433.52
Appearance :
Colorless liquid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Siponimod, which is an orally administered, selective modulator of sphingosine-1-phosphate (S1P) receptors. Siponimod is utilized in research related to multiple sclerosis (MS).

References : Gergely P. et al.: Br. J. Pharmacol., 167(5), 1035-47, 2012; Pan S. et al.: ACS Med Chem Lett., 4(3), 333-7, 2013; McGinley M. et al.: Ther Adv Neurol Disord. 2018 Jul 17;11, 1756286418788013, 2018; Behrangi N. et al.: Cells, 8(1):24, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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