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Siponimod-d11

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SL-11656

Siponimod-d11, >98%

CAS No. : [2104759-32-0]

Synonyms : BAF-312-d11

IUPAC Name : (E)-1-(4-(1-(((4-(Cyclohexyl-d11)-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid

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Chemical Properites
Mol. Formula :
C29H24D11F3N2O3
Mol. Weight :
527.67
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Siponimod-d11 is a deuterium-labelled version of Siponimod. This can be used as an analytical labelled reference standard. Siponimod is an orally administered, selective modulator of sphingosine-1-phosphate (S1P) receptors. Siponimod is utilized in research related to multiple sclerosis (MS).

References : Gergely P. et al.: Br. J. Pharmacol., 167(5), 1035-47, 2012; Pan S. et al.: ACS Med Chem Lett., 4(3), 333-7, 2013; McGinley M. et al.: Ther Adv Neurol Disord. 2018 Jul 17;11, 1756286418788013, 2018; Behrangi N. et al.: Cells, 8(1):24, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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