Siponimod (Z)-isomer diethylamine salt

SL-11659

Siponimod (Z)-isomer diethylamine salt, >98%

CAS No. : [2768181-14-0]

Synonyms : (Z)-Siponimod diethylamine salt

IUPAC Name : Diethylamine (Z)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylate

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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is a (Z)-geometric isomer impurity of Siponimod. The active form, known as (E)-Siponimod, is an orally administered, selective modulator of sphingosine-1-phosphate (S1P) receptors. Siponimod is used in research focused on multiple sclerosis (MS).

References : Gergely P. et al.: Br. J. Pharmacol., 167(5), 1035-47, 2012; Pan S. et al.: ACS Med Chem Lett., 4(3), 333-7, 2013; McGinley M. et al.: Ther Adv Neurol Disord. 2018 Jul 17;11, 1756286418788013, 2018; Behrangi N. et al.: Cells, 8(1):24, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.