Siramesine fumarate

SI-7243

Siramesine fumarate, >98% (HPLC)

CAS No. : [163630-79-3]

Synonyms : LU-28-179 fumarate

IUPAC Name : 1'-(4-(1-(4-Fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine] fumarate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Siramesine fumarate is a potent sigma‑2 agonist (IC₅₀ = 0.12 nM; 140‑fold σ₂ selectivity) that induces mitochondrial‑mediated cell death and shows anticancer activity.

References : Perregaard J. et al.: J. Med. Chem., 38(11), 1998-2008, 1995; Cesen M. H. et al.: Cell. Death Dis., 4(10), e818, 2013; Ostenfeld M. S. et al.: Autophagy, 4(4), 487-99, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.