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Sitagliptin-d4 phosphate

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SL-6551

Sitagliptin-d4 phosphate, >98% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [1432063-88-1]

Synonyms : MK-0431-d4 phosphate; MK0431-d4 phosphate

IUPAC Name : (R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl-d4)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate

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Chemical Properites
Mol. Formula :
C16H11D4F6N5O . H3PO4
Mol. Weight :
509.34
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Sitagliptin-d4 phosphate is a deuterium labelled version of Sitagliptin, which is an oral and highly selective DPP-4 inhibitor, used in the treatment of type 2 diabetes.

References : Karasik A. et al.: Curr Med Res Opin., 24(2), 489-496, 2008; Kim S. J. et al.: Diabetes 58(3), 641-651, 2009; Sangle G. V. et al.: Endocrinology 153(2), 564-573, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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