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Updated Product Catalog

CAS No. : [150374-95-1]
MDL No. : MFCD08461731
Synonyms : LY-544349 sodium; ONO-5046 sodium; EI-546 sodium
IUPAC Name : Sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 10MG | 120.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | 280.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | 550.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | 1050.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | 2250.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H21N2NaO7S | Mol. Weight : 456.44 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
References : Kawabata K. et al.: Biochem Biophys Res Commun., 177(2), 814-20, 1991; Toda Y. et al.: Int. J. Mol Med., 19(2), 237-43, 2007; Kono T. et al.: Mol Cell Biochem., 311(1-2), 87-92, 2008; Sahebnasagh A. et al.: J. Clin Pharm Ther., 45(6), 1515-1519, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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