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SK-124

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SI-7505

SK-124, >98% (HPLC)

CAS No. : [2760404-50-8]

IUPAC Name : 2-(2,6-Dimethoxy-4-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)phenyl)-5-ethyl-1,3,4-oxadiazole

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Chemical Properites
Mol. Formula :
C23H22N6O3
Mol. Weight :
430.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SK‑124 selectively inhibits SIK2 and SIK3 and promotes bone remodeling by elevating P1NP and CTX. These effects translate into increased bone formation and bone mass, making SK‑124 a useful probe for SIK‑dependent skeletal pathways.

References : Sato T. et al.: Proc. Natl. Acad. Sci. U S A., 119(50), e2214396119, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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