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SMD-3040 intermediate 1

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SI-7325

SMD-3040 intermediate 1, >98% (HPLC)

CAS No. : [3033110-45-8]

IUPAC Name : (1r,4r)-4-((7-(4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)-1H-pyrazol-1-yl)-2-azaspiro[3.5]nonan-2-yl)methyl)cyclohexane-1-carboxylic acid

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Chemical Properites
Mol. Formula :
C29H36N6O3
Mol. Weight :
516.65
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SMD‑3040 intermediate‑1 represents an upstream intermediate in the synthetic route to SMD‑3040. It contributes to constructing the ligand–linker architecture required for efficient SMARCA2 PROTAC formation.

References : Yang L. et al.: J. Med. Chem., 66(15), 10761-10781, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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