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SNS-032

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SI-7422

SNS-032, >98% (HPLC)

CAS No. : [345627-80-7]

Synonyms : BMS-387032

IUPAC Name : N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide

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Chemical Properites
Mol. Formula :
C17H24N4O2S2
Mol. Weight :
380.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SNS‑032 selectively targets CDK2, CDK7, and CDK9 with low‑nanomolar potency (IC50 = 4–62 nM). It effectively suppresses tumor‑cell growth through inhibition of transcriptional and cell‑cycle regulatory mechanisms, supporting its use in cancer research.

References : Misra R. N. et al.: J. Med. Chem., 47(7), 1719-28, 2004; Mukhopadhyay P. et al.: Cancer Res., 66(3), 1758-66, 2006; Chen R. et al. Blood., 113(19), 4637-45, 2009; Heath E. I. et al.: Invest New Drugs., 26(1), 59-65, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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