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SNT-207858

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SI-7267

SNT-207858, >98% (HPLC)

CAS No. : [1104080-42-3]

IUPAC Name : N-((R)-3-(2,4-Dichlorophenyl)-1-oxo-1-(4-(3-((R)-2-(pyrrolidin-1-yl)butoxy)pyridin-2-yl)piperidin-1-yl)propan-2-yl)pyrrolidine-1-carboxamide dihydrochloride

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Chemical Properites
Mol. Formula :
C32H43Cl2N5O3 • 2HCl
Mol. Weight :
689.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SNT-207858 selectively antagonizes MC4R with nanomolar potency (IC50 = 22 nM binding; 11 nM functional) and readily crosses the blood–brain barrier. Its pharmacological profile makes it suitable for probing CNS‑mediated melanocortin pathways.

References : Weyermann P. et al.: PLoS One, 4(3), e4774, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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