SNX-5422 mesylate

SI-5763

SNX-5422 mesylate, >98% (HPLC)

CAS No. : [1173111-67-5]

MDL No. : MFCD29924735

Synonyms : PF-04929113 mesylate

IUPAC Name : (1r,4r)-4-((2-Carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl glycinate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: SNX-5422 mesylate is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : SNX-5422 mesylate is a potent and selective Hsp90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC₅₀ of 37 nM. SNX-5422 mesylate has been discontinued because of ocular toxicity seen in animal models and in a separate phase I study.

References : Huang K. H. et al.: J. Med Chem., 52(14), 4288-4305, 2009; Yutaka Okawa. et al.: Blood 113(4), 846-855, 2009; Lamoureux F. et al.: Clin Cancer Res., 17(8), 2301-2313, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.