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Solcitinib

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SI-6285

Solcitinib, >98% (HPLC)

CAS No. : [1206163-45-2]

Synonyms : GSK-2586184; GLPG-0778

IUPAC Name : N-(5-(4-(3,3-Dimethylazetidine-1-carbonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H23N5O2
Mol. Weight :
389.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Solcitinib selectively targets JAK1 with low‑nanomolar potency (IC50 = 9.8 nM) and shows substantial selectivity over JAK2, JAK3, and TYK2. It is a valuable tool compound for investigating JAK1‑driven cytokine pathways in moderate‑to‑severe plaque‑type psoriasis.

References : Ludbrook V. J. et al.: Br. J. Dermatol., 174(5), 985-95, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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