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Sorafenib impurity C

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SL-9912

Sorafenib impurity C, >98%

CAS No. : [2204442-52-2]

IUPAC Name : Methyl 4-(4-(3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)phenoxy)picolinate

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Chemical Properites
Mol. Formula :
C27H23N5O6
Mol. Weight :
513.51
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Sorafenib, which is a new small molecule multi-kinase inhibitor for the treatment of patients with advanced renal cell carcinoma. It works by blocking the action of an abnormal protein that signals cancer cells to multiply and helps stop the spread of cancer cells.

References : Wilhelm S. M. et al.: Cancer Res., 64(19), 7099-109, 2004; El-Ashmawy N. E. et al.: Clin Exp Med., 17(2),185-191, 2017; Jin W. et al.: Oncol Rep., 37(1), 273-280, 2017; Li M. et al.: Br. J. Cancer 117(7), 974-983, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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