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Sotalol-d6

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SL-8930

Sotalol-d6, >98%

CAS No. : [1246912-17-3]

Synonyms : MJ 1999-d6

IUPAC Name : N-(4-(1-Hydroxy-2-((propan-2-yl-1,1,1,3,3,3-d6)amino)ethyl)phenyl)methanesulfonamide

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Chemical Properites
Mol. Formula :
C12H14D6N2O3S
Mol. Weight :
278.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Sotalol, which is an orally active, non-selective beta-adrenergic receptor blocker. It is a potent antiarrhythmic agent that can be utilized in the research of pediatric arrhythmias. Sotalol works by blocking beta-receptors and potassium KCNH2 channels. Additionally, it acts as an antiepileptic agent.

References : Reyes-Corral M. et al.: J. Pharmacol Exp. Ther., 369(1), 152-162, 2019; Xiaomei Li X. et al.: Pediatr Cardiol., 38(7), 1450-1455, 2017; Borowicz-Reutt K. K. et al. Pharmacol Rep., 73(2), 516-524, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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