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Sotorasib isomer 4

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Sotorasib isomer 4, >98%

CAS No. : [2252403-56-6]

IUPAC Name : 4-(S)-4-Acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C30H30F2N6O3
Mol. Weight :
560.61
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an isomer of Sotorasib, which is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib is being developed for the treatment of non-small-cell lung cancer (NSCLC).

References : Canon J. et al.: Nature, 575(7781, 217-223, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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