SP-27

SI-8075

SP-27, >98% (HPLC)

CAS No. : [3034805-75-6]

IUPAC Name : 5-(4-(4-(6-((2,4-Difluorobenzyl)amino)-4-((5-methyl-1H-pyrazol-3-yl)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)piperidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SP-27 is a PLK4‑selective PROTAC with low‑nanomolar degradation potency (DC₅₀ = 19.5 nM). Its ability to efficiently degrade PLK4 supports its use in mechanistic and therapeutic research related to PLK4‑driven breast cancer.

References : Sun Y. et al.: J. Med. Chem., 66(12), 8200-8221, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.