SPH-3127

SI-7160

SPH-3127, >98% (HPLC)

CAS No. : [1399849-02-5]

IUPAC Name : Methyl (3-(3-((R)-1-((R)-N-cyclopropylmorpholine-2-carboxamido)ethyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)propyl)carbamate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SPH-3127 is a potent oral renin inhibitor (IC₅₀ ≈ 0.4 nM) that effectively suppresses renin activity in biochemical and plasma assays. It shows clear antihypertensive effects and is well suited for hypertension‑related research.

References : Iijima D. et al.: J. Med. Chem., 65(16), 10882-10897, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.