SPH-5030

SI-7036

SPH-5030, >98% (HPLC)

CAS No. : [2364326-23-6]

IUPAC Name : (R,Z)-N-(4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)-7-ethoxyquinazolin-6-yl)-2-fluoro-3-(1-methylpyrrolidin-2-yl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SPH-5030 functions as a selective irreversible HER2 inhibitor with low‑nanomolar potency against HER2^WT (IC₅₀ = 3.51 nM) and EGFR^WT (IC₅₀ = 8.13 nM). It displays excellent activity against HER2 mutant variants, making it a valuable tool for cancer research.

References : Li D. et al.: J. Med. Chem., 65(7), 5334-5354, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.