SPL-707

SI-863

SPL-707, >98% (HPLC)

CAS No. : [2195361-33-0]

MDL No. : MFCD31657382

IUPAC Name : (S)-2-Cyclopropyl-N1-((S)-5,11-dioxo-3,5,10,11-tetrahydro-1H-spiro[benzo[d]pyrazolo[1,2-a][1,2]diazepine-2,1'-cyclopropan]-10-yl)-N4-(5-fluoro-2-methylpyridin-3-yl)succinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
25MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
100MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
250MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
500MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
Note: SPL-707 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We will respond promptly. Thank You!

Applications : SPL-707 is the first selective, orally active signal peptide peptidase-like 2a (SPPL2a) inhibitor with IC₅₀ of 77 nM, shows 25-fold selectivity over γ-secretase and SPP.

References : Velcicky J. et al.: J. Med. Chem., 61(3), 865-880, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.