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SR-2211

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SI-7536

SR-2211, >98% (HPLC)

CAS No. : [1359164-11-6]

IUPAC Name : 1,1,1,3,3,3-Hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol

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Chemical Properites
Mol. Formula :
C26H24F7N3O
Mol. Weight :
527.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SR-2211 selectively targets RORγ as a synthetic inverse agonist, demonstrating strong binding affinity (Ki= 105 nM) and functional inhibition (IC50≈ 320 nM). Its pharmacological profile supports its use in studies of RORγ‑mediated immune regulation.

References : Kumar N. et al.: ACS. Chem Biol., 7(4), 672-7, 2012; Song Y. et al.: Eur. J. Med. Chem., 116, 13-26, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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