SR-717 free acid

SI-6956

SR-717 free acid, >98% (HPLC)

CAS No. : [2375420-34-9]

IUPAC Name : 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SR‑717 free acid functions as a stable cGAMP‑mimetic STING agonist, activating the pathway with EC₅₀ values of ~2.1–2.2 µM in both WT and cGAS‑KO ISG‑THP1 cells. Its ability to stimulate STING‑dependent immune signaling underlies its antitumor effects.

References : Emily N. Chin et al.: Science, 369(6506), 993-999, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.