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SR-7826

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SI-7198

SR-7826, >98% (HPLC)

CAS No. : [1219728-20-7]

IUPAC Name : 1-(2-Hydroxyethyl)-3-(4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-1-phenylurea

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H21N5O2
Mol. Weight :
387.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SR-7826 selectively and orally inhibits LIMK1 (IC50 = 43 nM) and displays >100‑fold selectivity relative to ROCK and JNK kinases. Its potency and selectivity make it valuable for studying LIMK‑mediated actin dynamics and downstream signaling.

References : Yin Y. et al.: J .Med .Chem., 58(4), 1846-61, 2015; Henderson W. B. et al.: Sci. Signal., 12(587), eaaw9318, 2019; Yu Q. et al.: Br. J. Pharmacol., 175(11), 2077-2096, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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