Stavudine 5-O-beta-glucuronide-d3

SI-5871

Stavudine 5-O-β-glucuronide-d₃, >98% (HPLC)

Isotopic Purity : 98 atom % D

IUPAC Name : (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(((2S,5R)-5-(5-(methyl-d₃)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methoxy)tetrahydro-2H-pyran-2-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: Stavudine 5-O-β-glucuronide-d3is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : Stavudine 5-O-β-glucuronide-d₃ is a deuterium labelled version metabolite of Stavudine, which is an orally active nucleoside reverse transcriptase (NRT) inhibitor. Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.

References : Moyle G. J. et al.: Antivir Ther., 2(4), 207-218, 1997; Riddler S. A. et al.: Antiviral Res., 27(3), 189-203, 1995; La Rosa F. et al.: J. Alzheimers Dis., 72(2), 401-412, 2019; Ferraresi R. et al.: FEBS Lett., 580(28-29), 6612-6616, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.