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Stavudine-d4

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SI-5868

Stavudine-d4, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1219803-67-4]

Synonyms : d4T-d4

IUPAC Name : 1-((2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione-6-d

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: Stavudine-d4is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C10H8D4N2O4
Mol. Weight :
228.24
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Stavudine-d4 is a deuterium labelled version an analog of Stavudine, which is an orally active nucleoside reverse transcriptase (NRT) inhibitor. Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.

References : Moyle G. J. et al.: Antivir Ther., 2(4), 207-218, 1997; Riddler S. A. et al.: Antiviral Res., 27(3), 189-203, 1995; La Rosa F. et al.: J. Alzheimers Dis., 72(2), 401-412, 2019; Ferraresi R. et al.: FEBS Lett., 580(28-29), 6612-6616, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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