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SU-14813

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SI-8003

SU-14813, >98% (HPLC)

CAS No. : [627908-92-3]

IUPAC Name : (R,Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

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Chemical Properites
Mol. Formula :
C23H27FN4O4
Mol. Weight :
442.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SU-14813 inhibits several angiogenesis‑associated RTKs with low‑nanomolar potency, including VEGFR1, VEGFR2, PDGFRβ, and KIT. Its multi‑target activity makes it a valuable tool for studying RTK‑dependent tumor growth and vascular biology.

References : Patyna S. et al.: Mol. Cancer Ther., 5(7), 1774-82, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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