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Suberoylanilide-13C6 hydroxamic acid

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SL-732

Suberoylanilide-13C6 hydroxamic acid, >98% (CP)

Isotopic Purity : 99 atom % 13C

MDL No. : MFCD30146154

Related CAS No. : [149647-78-9] of the unlabelled compound

Synonyms : Suberanilohydroxamic acid-13C6; 13C6-SAHA

IUPAC Name : N1-Hydroxy-N8-(phenyl-13C6)octanediamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG1995.00
Back Order  Estimated to ship on 04 October 2026
10MG2995.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C813C6H20N2O3
Mol. Weight :
270.35
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a 13C- labelled version of Suberoylanilide hydroxamic acid-13C6, which is a potent inhibitor of HDAC activity and has undergone initial evaluation in several Phase I and II clinical trials. HDACs are enzymes that catalyse the removal of the acetyl moiety from the lysine residues of proteins, including the core nucleosomal histones. Cell culture studies demonstrating that vorinostat enhances the antitumour efficacy of radiation therapy or chemotherapy. It can be used as analytical reference standard.

References : Richon V. M.: Br. J. Cancer, 95(S1), S2, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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