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Sulfapyridine

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SI-7694

Sulfapyridine, >98% (HPLC)

CAS No. : [144-83-2]

IUPAC Name : 4-Amino-N-(pyridin-2-yl)benzenesulfonamide

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Chemical Properites
Mol. Formula :
C11H11N3O2S
Mol. Weight :
249.29
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Sulfapyridine, generated from sulfasalazine metabolism, is a sulfonamide antibiotic that inhibits P. carinii DHPS with an IC50 of 0.18 µM. Beyond its antimicrobial activity, it also exerts anti‑inflammatory and anti‑rheumatic effects.

References : Omoteyama K. et al.: Biochim. Biophys. Acta. Proteins. Proteom., 1867(1), 47-56, 2019; Andreasen J. J. et al.: APMIS, 96(6), 568-70, 1988; Hong Y. L. et al.: Antimicrob Agents Chemother., 39(8), 1756-63, 1995;Kim M. H. et al.: Immunopharmacol. Immunotoxicol., 22(2), 253-66, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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