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Sunitinib N,N-dimethyl-d4 impurity

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SL-1301

Sunitinib N,N-dimethyl-d4 impurity, >98% (CP)

Isotopic Purity : 98 atom % D

Related CAS No. : [326914-17-4] of the unlabelled compound

Synonyms : N,N-Dimethyl sunitinib-d4 hydrochloride

IUPAC Name : (Z)-N-(2-(Dimethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide-d4 hydrochloride

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Chemical Properites
Mol. Formula :
C20H19D4FN4O2 . HCl
Mol. Weight :
410.91
Appearance :
Yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Sunitinib (Sunitinib N,N-dimethyl-d4 impurity), which is a potent inhibitor of multiple tyrosine kinase receptors and exhibits potent antiangiogenic and antitumor activity. It is used for the treatment of Imatinib-resistant gastrointestinal stromal tumors and renal cell cancer.

References : Sun Li. et al.: J. Med. Chem., 46, 1116, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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