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Sunitinib N-oxide

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SL-1296

Sunitinib N-oxide, >98%

CAS No. : [356068-99-0]

IUPAC Name : (Z)-N,N-Diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethanamine oxide

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Chemical Properites
Mol. Formula :
C22H27FN4O3
Mol. Weight :
414.47
Appearance :
Yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Sunitinib N-oxide is a derivative of Sunitinib (SL-384), which is a potent inhibitor of multiple tyrosine kinase receptors and exhibits potent antiangiogenic and antitumor activity. It is used for the treatment of Imatinib-resistant gastrointestinal stromal tumors and renal cell cancer.

References : Chow L. Q. et. al.: J. Clin. Oncol., 25(7), 884, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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