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CAS No. : [2649467-57-0]
Synonyms : Suzetrigine (2S,3R,4R,5S) enantiomer
IUPAC Name : 4-((2S,3R,4R,5S)-3-(3,4-Difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxamido)picolinamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
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Mol. Formula : C21H20F5N3O4 | Mol. Weight : 473.40 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an enantiomer of Suzetrigine, which is an orally administered, highly selective inhibitor of NaV1.8 that functions as an analgesic agent. In addition, Suzetrigine acts as a blocker of sodium channel protein type 10 subunit alpha. Suzetrigine shows significant potential for research related to the management of acute pain following abdominoplasty and bunionectomy procedures.
References : Jones J. et al.: N.Engl J. Med., 389(5), 393-405, 2023; Zhang H. et al.: Biomed Chromatogr., 38(7), e5907, 2024; Yu G. et al.: Biopharm Drug Dispos., 45(2), 107-114, 2024; Qin H. et al.: Eur. J. Med. Chem., 254, 115371, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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