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SWE101

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SI-5493

SWE101, >98% (HPLC)

CAS No. : [2376322-12-0]

IUPAC Name : 4-(4-(3,4-Dichlorophenyl)-5-phenyloxazol-2-yl)butanoic acid

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Chemical Properites
Mol. Formula :
C19H15Cl2NO3
Mol. Weight :
376.23
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SWE101 is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH.

References : Kramer J. S. et al.: J. Med Chem., 62(18), 8443-8460, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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