SY-5609

SI-6909

SY-5609, >98% (HPLC)

CAS No. : [2417302-07-7]

Synonyms : CDK7-IN-3

IUPAC Name : (S)-7-(Dimethylphosphoryl)-3-(2-((6,6-dimethylpiperidin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)-1H-indole-6-carbonitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SY‑5609 selectively targets CDK7 with high affinity (Kd = 0.065 nM) and exhibits poor activity against related kinases, including CDK2, CDK9, and CDK12. Its potent CDK7 inhibition leads to apoptosis in tumor cells and supports its antitumor efficacy in preclinical studies.

References : Jason J. M. et al.: J. Med. Chem., 65(2), 1458-1480, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.