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Tadalafil bis(2-aminopropanoate) dimer impurity

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SL-9942

Tadalafil bis(2-aminopropanoate) dimer impurity, >98%

IUPAC Name : Dimethyl 3,3'-(ethane-1,1-diylbis(1H-indole-2,3-diyl))(2R,2'R)-bis(2-aminopropanoate) bis trifluoroacetate

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Chemical Properites
Mol. Formula :
C26H30N4O4 • 2CF3CO2H
Mol. Weight :
690.6
Appearance :
Yellow solid (hygroscopic)
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tadalafil, which is a PDE5 inhibitor. Tadalafil is used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH).

References : Blount M. A. et al.: Mol Pharmacol., 66(1), 144-152, 2004; Mostafa M. E. et al.: Urology 81(6), 1253-1260, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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