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SI-7232

Tagtociclib, >98% (HPLC)

CAS No. : [2460249-19-6]

Synonyms : PF-07104091

IUPAC Name : (1R,3S)-3-(3-(3-(Methoxymethyl)-1-methyl-1H-pyrazole-5-carboxamido)-1H-pyrazol-5-yl)cyclopentyl isopropylcarbamate

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Chemical Properites
Mol. Formula :
C19H28N6O4
Mol. Weight :
404.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tegtociclib selectively inhibits CDK2 with sub‑nanomolar potency (Ki = 1.16 nM) and demonstrates promising antitumor activity in cyclin E‑amplified cancer models.

References : Hoffman. R. L. In AACR Annual Meeting , DDT02, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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