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Taselisib

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SI-5338

Taselisib, >98% (HPLC)

CAS No. : [1282512-48-4]

MDL No. : MFCD26142641

Synonyms : GDC-0032; RG-7604

IUPAC Name : 2-(4-(2-(1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide

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Chemical Properites
Mol. Formula :
C24H28N8O2
Mol. Weight :
460.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Taselisib is a potent, next-generation β isoform-sparing PI3K inhibitor with antitumor activity.

References : Zumsteg S. Z. et al.: Clin Cancer Res., 22(8), 2009–2019, 2016; Marian M. Deuker et al.: Cancer Discov., 5(2), 143-153, 2015; Ndubaku O. C. et al.: J. Med Chem., 56(11), 4597-46, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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