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Tasquinimod

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SL-1635

Tasquinimod, >98%

CAS No. : [254964-60-8]

MDL No. : MFCD18251454

Synonyms : ABR-215050

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Chemical Properites
Mol. Formula :
C20H17F3N2O4
Mol. Weight :
406.36
Appearance :
Light yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tasquinimod is an allosteric modulator of HDAC4 with a Kd of 10–30 nM for the regulatory Zn2+ binding domain of HDAC4.

References : Isaacs J. T. et al.: Cancer Res., 73(4),1386-1399, 2013; Isaacs J. T. et al.: Oncotarget., 5(18), 8093-8106, 2014; Olsson A. et al.: Mol Cancer., 17, 9, 107, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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