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TCMDC-135051 TFA

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SI-6384

TCMDC-135051 TFA, >98% (HPLC)

CAS No. : [2571578-55-5]

IUPAC Name : Trifluoroacetic acid with 4-(2-(5-((diethylamino)methyl)-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-2-isopropylbenzoic acid (1/1)

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Chemical Properites
Mol. Formula :
C29H33N3O3 • CF3CO2H
Mol. Weight :
585.62
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : TCMDC‑135051 TFA selectively targets PfCLK3, leading to transcriptional disruption and inhibition of the trophozoite‑to‑schizont transition. It reduces transmission to the mosquito vector and displays antiparasiticidal potency with an EC50 of 320 nM.

References : Alam M. M. et al.: Science., 365(6456), 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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