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Telmisartan acyl-β-D-glucuronide

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SL-5074

Telmisartan acyl-β-D-glucuronide, >98%

CAS No. : [250780-40-6]

Synonyms : 1-[4'-[(1',4-Dimethyl-2-propyl[2',6-bi-1H-benzimidazol]-1-yl)methyl][1,1'-biphenyl]-2-carboxylate] β-D-glucopyranuronic acid; Telmisartan glucuronide

IUPAC Name : (2R,3R,4R,5S,6R)-6-((4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C39H38N4O8
Mol. Weight :
690.75
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a glucuronide metabolite of Telmisartan, which is an angiotensin II antagonist receptor blocker (ARB), used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

References : Benson S. C. et al.: Hypertension, 43(5), 993-1002, 2004; Yoshida T. et al.: Diabetologia, 49(12), 3094-3099, 2006; Fujimoto M. et al.: FEBS Lett, 576(3), 492-497, 2004; Sugimoto K. et al.: Hypertension, 47(5), 1003-1009, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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