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Temozolomide impurity 1

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Temozolomide impurity 1, >98%

IUPAC Name : 3,3-Diamino-2-(phenyldiazenyl)acrylamide and 3-Amino-3-imino-2-(phenyldiazenyl)propanamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C9H11N5O
Mol. Weight :
205.22
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Temozolomide, which is an oral active DNA alkylating agent that crosses the blood-brain barrier and induces autophagy and apoptosis. It is effective against tumors with low O6-alkylguanine DNA alkyltransferase and intact mismatch repair, exhibiting both antitumor and antiangiogenic properties.

References : Tentori L. et al.: Blood, 99(6), 2241-4, 2002; Mathieu V. et al.: Neoplasia, 10(12), 1383-92, 2008; Perazzoli G. et al.: PLoS One 10(10), e0140131, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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