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Teneligliptin-d8

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SL-11695

Teneligliptin-d8, >98%

CAS No. : [1391012-95-5]

Synonyms : MP-513 d8

IUPAC Name : ((2S,4S)-4-(4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone

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5MGRequest A Quote
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Chemical Properites
Mol. Formula :
C22H22D8N6OS
Mol. Weight :
434.63
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Teneligliptin-d8 is a deuterium-labelled version of Teneligliptin. This can be used as an analytical labelled reference standard. Teneligliptin is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor. Teneligliptin is effective in improving blood glucose levels and may be utilised in studies concerning type 2 diabetes mellitus.

References : Yoshida T. et al.: Bioorg Med Chem., 20(19), 5705-19, 2012; Guo D. et al.: Metabolism 107, 154232, 2020; Zhang G. L. et al.: World J. Diabetes, 15(4), 724-734, 2024; Fukuda-Tsuru S. et al.: Eur. J. Pharmacol., 723, 207-15, 2014; Zhang Z. et al.: Biomed Pharmacother., 109, 468-474, 2019; Peng W. et al.: Arch Biochem Biophys., 683, 108238, 2020; Liu X. et al.: Int. Immunopharmacol., 73, 57-63, 2019; Elumalai S. et al.: Free Radic Biol Med., 160, 618-629, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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