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Teneligliptin hydrobromide

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SI-4582

Teneligliptin hydrobromide, >98% (HPLC)

CAS No. : [906093-29-6]

MDL No. : MFCD23098790

Synonyms : MP-513 hydromide

IUPAC Name : ((2S,4S)-4-(4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone hydrobromide

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Chemical Properites
Mol. Formula :
C22H30N6OS . 2.5 HBr
Mol. Weight :
628.86
Appearance :
Light beige solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Teneligliptin hydrobromide is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM.

References : Fukuda-Tsuru S. et al.: Eur. J. Pharmacol., 696(1-3), 194-202, 2012; Ideta T. et al.: Int. J. Mol Sci., 16(12), 29207-29218, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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