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Tenofovir alafenamide-d7 (isopropyl-d7)

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SL-1874

Tenofovir alafenamide-d7 (isopropyl-d7), >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [2131003-64-8]

Related CAS No. : [379270-37-8] of the unlabelled compound

Synonyms : N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-alanine-d7 1-methylethyl ester

IUPAC Name : Propan-2-yl-d7 (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate

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Chemical Properites
Mol. Formula :
C21H22D7N6O5P
Mol. Weight :
483.51
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tenofovir alafenamide-d7 is a deuterium labelled analog of Tenofovir alafenamide, it is a prodrug of Tenofovir, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Murphy R. A. et al. Int. J. Mol. Sci.18(3), 2017; Musumeci G. et al. Sci. Rep. 7, 41018, 2017; Wahl A. et al. Sci. Rep.7, 41098, 2017; Menne S. et al.: J. Antimicrob Agents Chemother., 49(7), 2720-2728, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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