Tenofovir alafenamide O-desphenyl D-alanine-d7

SL-1885

Tenofovir alafenamide O-desphenyl D-alanine-d₇, >96% (CP)

Isotopic Purity : 98 atom % D

Related CAS No. : [376633-26-0] of the unlabelled compound

Synonyms : N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-methylethyl ester-d₇ (isopropyl-d₇); GS-7485-d₇

IUPAC Name : P-((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)-N-((R)-1-oxo-1-((propan-2-yl-d₇)oxy)propan-2-yl)phosphonamidic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : It is a deuterium labelled prodrug of PMPA, phenyl monophosphoramidate, and is a Tenofovir derivative, an acyclic phosphonate nucleotide analog; reverse transcriptase inhibitor. Used as an anti-HIV agent.

References : Shaw J. P. et al.: Pharm. Res., 14, 1824,1997; Wyles D. et al.: Clin Infect. Dis., 40, 174, 2005; Peng J. et al.: J. Clin. Pharmacol., 46, 265, 2006; Seminari E. et al.: J. Antimicrob. Chemother., 60, 831, 2007; Lee W. et al.: Antimicrob. Agents Chemother., 49, 1898, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.