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Tenofovir dibenzyloxy isopropyl carbamate

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SL-1866

Tenofovir dibenzyloxy isopropyl carbamate, >98%

CAS No. : [1391052-09-7]

Synonyms : [[(1R)-2(6-Isopropylaminocarbamate-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid dibenzyl ester

IUPAC Name : Isopropyl (R)-(9-(2-((bis(benzyloxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)carbamate

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Chemical Properites
Mol. Formula :
C27H32N5O6P
Mol. Weight :
553.55
Appearance :
Brown gum
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a dibenzyl protected analog of Tenofovir, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Murphy R. A. et al. Int. J. Mol. Sci.18(3), 2017; Musumeci G. et al. Sci. Rep. 7, 41018, 2017; Wahl A. et al. Sci. Rep. 7, 41098, 2017; Menne S. et al.: J. Antimicrob Agents Chemother., 49(7), 2720-2728, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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