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CAS No. : [1428064-91-8]
Synonyms : SM-04755
IUPAC Name : N-(6-Methoxypyridin-3-yl)-5-(5-(piperidin-1-ylmethyl)pyridin-3-yl)-1H-indazole-3-carboxamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C25H26N6O2 | Mol. Weight : 442.52 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Teplinovivint is a potent small‑molecule inhibitor of the Wnt signaling pathway, specifically targeting CDC-like kinase 2 (CLK2) to suppress β‑catenin–driven transcription. It demonstrates strong anti‑inflammatory and chondroprotective activity, reduces pro‑inflammatory cytokines, and promotes cartilage regeneration, making it a promising therapeutic candidate for osteoarthritis and other Wnt‑dependent degenerative diseases.
References : Sun Y. et al.: J. Med. Chem., 67(6), 4603-4623, 2024.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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