Tepotinib

SL-9999

Tepotinib, >98%

CAS No. : [1100598-32-0]

Synonyms : EMD-1214063

IUPAC Name : 3-(1-(3-(5-((1-Methylpiperidin-4-yl)methoxy)pyrimidin-2-yl)benzyl)-6-oxo-1,6-dihydropyridazin-3-yl)benzonitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Tepotinib is an orally active, highly selective, reversible ATP-competitive inhibitor of c-Met. It demonstrates an IC50 value of 3 nM and exhibits over 200-fold selectivity for c-Met compared to IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib effectively inhibits c-Met phosphorylation and promotes autophagy. Additionally, it has demonstrated antitumor activity.

References : Bladt F. et al.: Clin Cancer Res., 19(11), 2941-2951, 2013; Zhan N. et al.: Gene Expr., 18(2), 135-147, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.