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Terlipressin dimer (Gly12-Gly1)

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Terlipressin dimer (Gly12-Gly1), >95%

Synonyms : Terlipressin dimer chain elongation structure

IUPAC Name : H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (disulfide bridge between Cys4-Cys9 and Cys16-Cys21)

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C104H145N31O30S4
Mol. Weight :
2437.73
Appearance :
White lyophilized powder
Melting Point :
Not available
Solubility :
Freely soluble in H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Terlipressin, which is a vasopressin analog distinguished by potent vasoactive properties. As a highly selective agonist of the vasopressin V1 receptor, Terlipressin decreases splanchnic blood flow and portal pressure, effectively managing acute variceal bleeding. Additionally, Terlipressin demonstrates anti-inflammatory and anti-oxidative effects, and holds significant potential for research related to hepatorenal syndrome and norepinephrine-resistant septic shock.

References : Zi-Meng L. et al.: Exp Ther Med., 14(1), 260-266, 2017;
Yeun Tarl Fresner N. et al.: Int. J. Cardiol., 222, 135-140, 2016; Xiqiang L. et al.: Oncotarget., 7(43), 69276-69290, 2016; Xinmiao Z. et al.: Medicine (Baltimore). 97(48):e13437, 2018; Alastair O'Brien et al.: Lancet., 359(9313), 1209-10, 2002.

Storage : Keep container tightly closed under nitrogen or argon and store at -20oC for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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