tert-Butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-oxopropan-2-yl)carbamate

SL-8967

tert-Butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-oxopropan-2-yl)carbamate, >98%

CAS No. : [149709-58-0]

Synonyms : Sacubitril impurity 43; Sacubitril RC 4; Valsartan impurity 22; (Sacubitril impurity 22)

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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity of Sacubitril, which is a potent NEP inhibitor. Sacubitril is a key component of the heart failure medication LCZ696.

References : Ksander G. M. et al.: J. Med. Chem., 38(10), 1689-700, 1995; Voors A. A. et al.: Expert Opin Investig Drugs 22(8), 1041-1047, 2013; von Lueder T. G. et al. Circ Heart Fail. 8(1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.